One thing to be aware of is if you use messages.log to track IRIS.DAT growth the shrinking of IRISTEMP either through a delete or reset will throw off those numbers.
@Timo.Lindenschmid's point is a good one. Setting a max size can be done from SMP or in %SYS with ^DATABASE but that likely means you will have issues sooner.
MaxIRISTempSizeAtStart documentation.
iris session [INSTANCE] -U %sys ALL^%SS would give you the PID,namespace, routine, CPU and globals.
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I would try d ALL^%SS for CPU. d ALL^%SS is used in the ^pButtons report.
Due to shared memory it is hard to assign memory to much past the instance of Cache or IRIS.