Sure, you can interpret Intersystems IRIS in any way it works for your application, but in this contest, we want to focus on REST API on Intersystems IRIS side. That means you either use any internal 6 api (Atelier, UIMA, iKnow, DocDB, MGMNT, BI, Monitoring) or any installed from Open Exchange or build your own with Swagger and/or ObjectScript.

Updated the post regarding the list of internal REST API:

Or use any IRIS out-of-the-box REST API which you can check on  http://yourserver:port/api/mgmnt/

http://localhost:52773/api/mgmnt/

Amongst them are:

Atelier API: /api/atelier

IRIS BI API: /api/deepsee

DocDB API :/api/docdb

IRIS NLP(iknow) API: /api/iknow

Monitoring API: /api/monitor

Swagger Management API: /api/mgmnt

UIMA API: /api/uima